This study was undertaken to determine whether grape seed extracts (GSE) that contain powerful vasodilator phenolic compounds lower blood pressure in subjects with the metabolic syndrome. The subjects were randomized into 3 groups—(a) placebo, (b) 150 mg GSE per day,…
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Study Shows Relationship Between MegaNatural and Therapeutic Strategies in Alzheimer's Disease
Results of a new study published in the Journal of Neuroscience have exciting implications for the future use of a unique new grape seed extract to inhibit the development of Alzheimer’s disease and other cognitive impairments. Continue reading →
Mechanism of the Endothelium-Dependent Relaxation Evoked by a Grape Seed Extract
GSEs (grape seed extracts) which contain polyphenolic compounds cause an endotheliumdependent relaxation of blood vessels. The aim of the present study was to examine the mechanisms involved in this response. A well-characterized GSE was applied to rabbit aortic rings suspended…
Grape Seed Extract Induced Nitric Oxide Mediated Endothelial Dependent Relaxation Through AKT/PI3 Kinase Pathway
Oral administration of grape seed extract (Meganatural-BP Patent pending) (GSE) lowered the blood pressure in human subjects with the metabolic syndrome. We tested the hypothesis that GSE caused an endothelium dependent relaxation (EDR) in aortic rings from New Zealand White…
Effects of Grape Seed Extract in Subjects with Pre-Hypertension
This study was undertaken to determine whether grape see extracts (GSE) which contain powerful vasodilator phenolic compounds lower blood pressure (BP) in subjects with pre-hypertension. The subjects were randomized into a placebo or an experimental group (GSE at a dose…